From the Doctor’s Desk: Salivary Hormone Testing Backed by Science

Testing hormones through saliva is backed by science. But don’t take my word for it. In fact, it is well supported in the medical literature and is the right thing to do.  Below are links to several abstracts regarding salivary hormone testing. Read them for yourself and learn about the science behind this form of hormone testing.

• Belkien LD, Bordt J, Moller P, Hano R, Nieschlag E. Estradiol in saliva for monitoring follicular stimulation in an in vitro fertilization program. Fertil Steril 1985;44:322.
• Bolaji II, Tallon DF, O’Dwyer E, Fottrell PF. Assessment of bioavailability of oral micronized progesterone using a salivary progesterone enzymeimmunoassay. Gynecol Endocrinol 1993;7:101-110.
• Campbell BC, Ellison PT. Menstrual variation in salivary testosterone among regularly cycling women. Horm Res 1992;37:132-136.
• Aardal-Eriksson E, Karlberg BE, Holm AC. Salivary cortisol- and alternative to serum cortisol determinations in dynamic function tests. Clin Chem Lab Med 1998;36:215-222.

These articles are published in well-respected journals; and if you notice, they are not recent.  Salivary testing of hormones has been well published in the medical literature for some time now.

Here are a few quotes from these studies:

• “…salivary cortisol may be used as an alternative parameter in dynamic endocrine tests.”
• “…assessment of ovarian function…can be performed precisely with the saliva estradiol assay.”
• “…saliva collection has provided the medical and research community with an excellent medium for the monitoring of plasma steroid levels.”

Nowhere else in medicine do we blindly treat people without assessing a baseline and post treatment level(s). Balance is the key; not one individual hormone. Unfortunately, the medical field is very slow to learn and change.

From the Doctor’s Desk: Health and Wellness Defined

Definitions.

Health can best be defined as the absence of disease.  Wellness is best defined as the existence of positive health.  So health and wellness can be best defined as the absence of disease in the presence of positive health.

Why the focus on health and wellness these days? I think modern medicine gets a failing grade. Obesity is epidemic in the American culture today. One of my patients knew that her weight was not healthy. However, her previous physician told her that she should learn to live with her new heavier weight and maybe the weight would level out. That statement haunted her and led her to find a physician who offered her more hope and solutions.

Health and wellness cannot be achieved through a traditional, allopathic (Western modern medicine) medical approach. Why? Western modern medicine (we’ll call it traditional for our purposes) uses a disease-focused model utilizing pharmaceuticals. Pharmaceuticals block biochemical reactions, produce mitochondrial toxins, and deplete important nutrients. There is no positive health there.

In fact, the 4^th – 6^th leading cause of death is from prescription drugs (Mol Aspects Med. 2005 Aug-Oct;26(4-5):363-78). In contrast, functional medicine is a health and wellness model utilizing natural substances found in the body to enhance cellular processes. A health and wellness model looks to work with the body, to facilitate metabolic reactions and optimize physiologic function (The principles of metabolic therapy for heart disease. Heart, Lung and Circulation 2003; 12:S55-S62).

In some ways, the two are complementary; but in many ways, the two are not. I am not advocating a boycott of traditional medicine. In fact, I still practice some traditional medicine when disease exists.

The key is this — does disease exist or not?  If disease doesn’t exist, and health and wellness or health restoration is your goal, then a functional or integrative approach is the way to go to facilitate and optimize physiologic function.

So, what is a functional medicine approach?  To help define functional medicine, let’s look at a few examples.

The traditional medicine approach.

Metformin or Glucophage is a well-recognized drug used to treat diabetes.  Metformin works to improve insulin sensitivity and thus facilitate glucose uptake inside the cells.  Type II Diabetes is marked by very poor insulin sensitivity and thus blood sugar rises.  Traditional medicine prescribes Metformin to provide a 13% improvement in insulin sensitivity.

Remember, pharmaceuticals block biochemical reactions.  Metformin reduces folic acid and vitamin B12 and can elevate homocysteine. Elevated homocysteine levels increase blood clot risk (this is one of the ways that birth control pills increase blood clot risk).  Diabetics and those with insulin resistance are already at an increased risk of blood clots. Can you see how the treatment is piling on in this situation?

The functional medicine approach.

Let’s contrast that with a functional medicine approach. Vitamin D deficiency is rampant today. Vitamin D deficiency has been implicated in heart failure, myocardial dysfunction, sudden cardiac death, and is required for normal insulin release and glucose control.  Remember the 13% for metformin? Higher vitamin D levels resulted in a 60% improvement in insulin sensitivity (Chiu K., et al., “hypovitaminosis D is associated with insulin resistance and beta cell dysfunction,” Amer Jour Clin Nutr  2004).

Remember, functional medicine works with and facilitates the body’s functions. Vitamin D does not block any biochemical reactions, nor does it interfere with any. Thus, there is no negative effect comparable to Metformin. Now, too much of a good thing can be a problem. Too much Vitamin D can elevate calcium. Because of this, Vitamin D should be prescribed under the watchful eye of a physician.

Why do I do what I do?

Amazing results — as naturally as possible. This is why I practice functional medicine. This is why I created Seasons. A health and wellness model, through functional medicine, works with the body to enhance and optimize physiologic function.  Health and health restoration can only be achieved by working with the body. Let’s get out of the way and let the body heal itself.

From The Doctor’s Desk: Wellness Is Not Band-Aid Medicine

So you wake up one day and you have symptoms. You select a doctor, make an appointment, recite your symptom list, receive a diagnosis, get a prescription, take the prescription and hope that the prescription gets rid of the symptoms.

But the question is this: Are you well?

Symptom relief medicine is great, but it is reactive medicine. I call this band-aid medicine. Just throw a band-aid on it in 5-10 minutes and ignore the real underlying cause. You can relieve symptoms with band-aids, but if the cause is left unchecked (usually an imbalance of some sort), then disease will be the result.

I like to use symptoms as clues to finding the cause. I call it proactive medicine. Symptoms are the result of imbalance. Disease is the result of ignoring the symptoms. It is a progressive cycle: imbalance, symptoms, disease.

Balance is the key.  As I said above, symptoms are the result of imbalance. Medicine today has lost site of this. In the fast pace of the typical doctor’s office (even mine many years ago), all we have time for is symptom focus and treatment. There is no time for focus on cause.

You don’t have to look to far to see the importance of balance.  Look at our bodies.  They are all about balance:  two eyes, two ears, two legs…you get the picture.  This balance is by design. We should not lose sight of the fact that symptoms are the body crying out for help.

Symptoms reveal imbalances, and the imbalances can be quite diverse. They can include hormones: Estrogen/Progesterone, Thyroid/Cortisol, Growth Hormone/Cortisol, just to name a few. But imbalances can involve more than just our hormones. Neurotransmitters can be imbalanced. Have you ever heard of anxiety or depression? Neurotransmitters involve serotinin, glutamic acid, and nor-epinephrine just to name a few.  And no, anxiety and/or depression are not the result of a SSRI deficiency.

Even Fats can be imbalanced.  Everybody has heard of Omega 3.  Omega 3’s are anti-inflammatory, they lower cholesterol and are good for the skin. But have you heard of Omega 6 fats. Omega 6’s are pro-inflammatory. Americans have excessive Omega 6’s in our high processed diets. The typical American diet is 24 to 1 ratio of Omega 6 to Omega 3. A healthy ratio should be 3 to 1.

Symptoms are the body’s way of asking for help. Let’s start listening.

From The Doctor’s Desk: Wrinkles and Hearts

“If wrinkles must be written on our brows, let them not be written upon the heart. The spirit should never grow old.” — James A. Garfield, 20th President of the United States.

I read that quote by President Garfield the other day and it occurred to me how important his statement was in my practice of medicine. What causes wrinkles? What causes the spirit to grow old? What can damage the heart? The answer is stress. Stress is not something that just exists. Stress is not just a term used to describe forces applied as in engineering. Stress is real and it affects our hearts. Stress kills.

What impact does stress have on the health of our heart?

• 43% of all adults suffer stress related adverse health effects.
• 75-90% of all visits to primary care physicians are stress-related.
• Stress is directly linked to heart disease according to a new study from University College London.

The interesting thing about stress? It’s not just external. Stress is both external and internal. There is stress of day-to-day life. And then there is the silent physiologic stress. The internal stress occurs in the form of obesity, food sensitivity, and inflammation to name a few.

How is stress affecting you? Ask your heart. Focus on keeping your heart healthy by limiting and relieving your stress this Valentine’s Day. While we can’t always eliminate the causes of stress in our life, we can control how we allow it to affect us!

My recommendations?

• Make good food choices to give your body the right kind of energy that lasts and helps you work and feel better.
• Get regular exercise. It boosts your metabolism, fights fatigue, and even elevates your mood helping you to cope with stress more effectively.
• Take time to meditate and pray.
• Take a break and relax whether it’s a soak in the tub or a good book.

Take care of your heart. That’s the best gift you can give those you love!

Related articles by Zemanta

• Marcia G. Yerman: A New Recipe for Heart Health (huffingtonpost.com)
• Bill Clinton says lack of sleep added to heart problem (ctv.ca)
• Easy Tips for Reducing Stress (dirjournal.com)
• Stress `can cause heart damage’ (telegraph.co.uk)

From The Doctor’s Desk: The Moral of the Story? Hormone Balance Key To Reducing Breast Cancer Potential.

I have four kids that range in age from four to eleven. One of my favorite things to do is read them a great story. So today, let’s talk about some very important stories and the moral each one presents.

The story about breast cancer potential has more characters than just estrogen and progesterone as we discussed in my last post. There are other hormones that are integral characters in that story also. As you will learn in this post, the moral to the breast cancer story is balance — balance between all the hormones in your body.

The Story On Dehydroepiandrosterone (DHEA) — Say That One Three Times Fast!

DHEA, a testosterone precursor, is a hormone produced by the adrenal glands and plays a part in breast protection. DHEA plays an important role in supporting the immune system. DHEA stimulates the production of good T-helper lymphocytes-1 and their associated good cytokines: interferon, Interleukin-2 and Tumor Necrosis Factor-beta. This is in contrast to the bad T-helper lymphocytes-2 and their bad cytokines. DHEA levels typically decline as we age. The decrease in DHEA levels are inversely correlated with increasing age-related disease. The strength of this correlation is yet to be determined, but the decline in immune system due to low DHEA is clear. So where does that leave DHEA? Individuals with low DHEA levels have more disease, and in this case, more breast cancer. The moral of this story? Low DHEA = a compromised immune system = breast cancer vulnerability.

The Story On Melatonin — The Sandman Hormone.

Melatonin is the hormone that regulates your sleep cycle. It is produced from the pineal gland in the brain. Low melatonin levels have been linked to breast cancer through the additional benefits of melatonin. Melatonin boosts the immune system, decreases estrogen and progesterone production, and acts as an anti-oxidant. Bench studies (non-human studies) have shown significant increase risks of breast cancer with low melatonin levels. Can you guess what happens as we age? Yes, you guessed it. Our melatonin levels fall. Ever talk to a post-menopausal woman? Most women of that age have sleep-related complaints. The moral of this story? Low melatonin = a compromised immune system = breast cancer vulnerability.

The Story on Thyroid — The Energy Hormone.

How about the thyroid hormone?  The breast cancer link reaches to all hormones and everything seems to involve the thyroid these days! T4 (or better known as synthroid, levoxy, levothryoixine) is one of the most prescribed medicines today. But T4 is a very weak thyroid hormone. In fact, the body is looking for T3, a result of T4 to T3 conversion. The problem is that many individuals don’t convert T4 to T3 well. (Very often I see patients who have been on synthroid for years without symptomatic improvement even though their “levels” are said to be “good”.  I digress. That’s a subject for another post. Let’s get back to the breast cancer link.) Low T4 and T3 levels result in low sex hormone binding globulin levels (SHBG). SHBG is how some hormones are transported. When SHBG levels drop, the free availability of the hormone it transports goes up. In this case, the levels of free estradiol go up. Remember the negative breast implications of estrogen dominance from last weeks post (link)? The moral of this story? Low thyroid = low SHBG = high estradiol = estrogen dominance = breast cancer vulnerability.

The Story On Insulin — The Sugar Storer

Finally, Insulin. Insulin’s primary role is in the storage of glucose. However, due to the large percentage of simple or refined sugars in our diet, insulin resistance has become a major epidemic, and, yes, insulin resistance increases the risk of breast cancer. How, you ask? High simple sugars leads to insulin resistance and PCOS (Polycystic Ovarian Syndrome). As a result, estrogen dominance and excess testosterone are produced which leads to weight gain. Remember that fat cells produce even more estrogen and estrogen stimulates breast cell growth (link). Young women will start their cycles at an earlier age and thus will increase their lifetime exposure to estrogen without appropriate progesterone balance. And to make matters worse, traditional therapy with birth control pills for these young women increases the breast cancer risk even further. The moral of this story? Insulin resistance = estrogen dominance = breast cancer vulnerability.

Change The Ending Of The Story.

Just because any of these hormone deficiencies might produce in you symptoms which you recognize in this post doesn’t mean that you are going to have breast cancer. However, the sooner you seek hormone balance, the quicker you are going to lower your breast cancer vulnerability/potential. As you can see, the hormonal symphony is what is important. Balance! When your hormones are balanced, the result is a symphony, and in turn, your body is in tune and makes beautiful music. But when your hormones are not balanced, then…well, you know the ending of that story.

From The Doctor’s Desk: Hormone Imbalance A Contributing Factor In Breast Cancer

Hormone Replacement Therapy (HRT) increases breast cancer. Have you read headlines like that? Or perhaps you were told that HRT caused someone’s breast cancer.

Do hormones really cause or lead to breast cancer? Think about this: every women continues to produce hormones, even after menopause. So, it cannot be that hormones in and of themselves cause cancer. Scientific evidence indicates that synthetic hormones and hormone imbalance do contribute to breast cancer.

The ABC’s of Estrogen.

Estrogen’s effects in the body are regulated through two different kinds of receptors: alpha and beta receptors. Estrogen-alpha receptors stimulate breast cell growth. Estrogen-beta receptors inhibit breast cell growth.

• Estradiol, the most potent estrogen, equally stimulates alpha and beta receptors = growth stable
• Estrone, the second most potent estrogen, stimulates alpha receptors 5:1 over beta receptors = pro growth
• Estriol, the weakest variety of estrogen, actually stimulates beta receptors 3:1 = growth inhibitory

The key element here is balance of hormones. Higher levels of estrone present in your body (produced by fat cells) result in more breast stimulation. Higher levels of estriol present in your body results in less breast cell stimulation and, therefore, breast protection. Estriol = Good. Estrone = Bad. If you have heard of someone developing breast cancer after starting Premarin, there’s a logical explanation for that. Guess what Premarin is loaded with? Premarin contains (48%) estrone (estrone = bad = breast cell stimulation).

Here are some more ugly facts about Premarin, also know as conjugated equine estrogen. Premarin actually decreases estrogen beta receptors. So, if you take Premarin, then you are taking high doses of estrone (estrone = bad) and decreasing your estrogen receptors that inhibit breast cell growth. In a nutshell: you are taking more of the bad estrogen and decreasing your amount of the good estrogen. This equates to a prime set up for breast cancer.  Don’t take my word for it. See the wonderful article by Kent Holtorf.

Progesterone: The Growth-Inhibitor Hormone

The confusion out there about estrogen and breast cancer is bad enough, but the confusion is even greater on the subject of progesterone.

Pregesterone is the key hormone in the second half of a woman’s cycle. Estrogen is the dominant hormone in the first half of your cycle (estrogen = growth = growth of the uterine lining to support implantation of an egg). The counteractive hormone to this growth phase is progesterone (progesterone = no growth = sloughing off of the uterine lining). It’s the amazing and fascinating way that woman was created.

Synthetic progestins, often prescribed, are NOT the same as the progesterone your body produces. Just look at the structure and you see that they are not. The one thing they do have in common is they both protect the lining of the uterus against excessive estrogen growth. But, that is where the similarities end.

While there are many differences between the two, our focus here will be on the difference in breast cancer potential. Simply stated, synthetic progestins are pro-breast cancer and bioidentical progesterone is breast protective. The Women’s Health Initiative (link) revealed a 26% increase in breast cancer as a result of taking synthetic progestin. The Nurse’s Health Study (link) found that synthetic progestins tripled breast cancer risk over that of estrogen only. The use of Provera, a synthetic progestin and component of Prempro, has been shown to increase the risk of breast cancer by 800%!

The statistics for bioidentical progesterone are the opposite. Bioidentical progesterone has many positive breast benefits:

• Progesterone decreases estrogen production
• Progesterone moves estradiol to weaker estrone
• Progesterone moves estrone to inactive (sulfated) form
• Progesterone moves estrone to weakest/safest estriol
• Progesterone down-regulates estrogen receptors all together
• Progesterone activates the cancer protection gene, p53

The idea that progesterone is a safer alternative to synthetic progestins is not new at all.  As early as the early 80’s, there has been a call for safer progesterone over synthetic progestin counterparts. In 1981, nearly 30 years ago, L.D. Cowan showed that just having low progesterone levels increases the risk of premenopausal breast cancer risk 5.4 times.

Unfortunately, progesterone-deficient states, (or estrogen dominance) are very common in women today as a result of many factors: being overweight, PCOS, environmental xenoestrogens, excessive estrogen therapy, and perimenopause. Another study, showed progesterone to have a 400% decreased breast growth rate.

The Scientific Evidence Is Clear.

The evidence in the scientific literature is clear with regards to estrogens, progesterone, and hormone balance.

Bioidentical and synthetic hormones should NOT be used interchangeably. They are not equal. They have very different physiologic effects on the breast:  synthetic progestins (Provera notably) increase breast cancer (800%) and bioidentical progesterone protects against breast cancer (400% decrease breast growth rate).

Estrogen therapy is not for everybody and is definitely not a panacea drug; in fact estrogen dominance is a major contributor to breast cancer risk. But if estrogen therapy is needed, then estriol (Estriol = good) is the best.

Hormone balance is the key. Without estrogen and progesterone balance, a women’s cycles are irregular, and infertility can be a big problem.

You know, once we understand hormones and the balancing cycle between estrogen and progesterone, it makes perfect sense that imbalance would cause breast problems. And the scientific evidence indicates just that. In honor of Breast Cancer Awareness Month, it’s time make sure your hormones are balanced and protect yourself from breast cancer.

From the Doctor’s Desk: Think Pink — It’s Breast Cancer Awareness Month!

I love the change of seasons. I particularly love fall in the South. The oppressive heat of summer gives way to crisp, cool mornings, green leaves give way to brilliant colors, and college football returns.  But, October is even more special than that. October brings attention to one of the greatest fears of women — breast cancer.  October is Breast Cancer Awareness month.

There is much to be excited about in the arena of breast cancer treatment. Earlier detection, minimally invasive surgery, and high survival rates head the list. Credit needs to be given to the great work of many organizations like the Susan G. Komen Foundation and many researchers and physicians around the world.

But, breast cancer has not given up.

Let’s look specifically at the most current statistics of breast cancer. The lifetime probability of women developing breast cancer (2003-2005) is 1 in 8.  That amounts to about 185,000 women annually. Breast cancer accounts for 27% of all cancers in women. Breast cancer accounts for 15% of all cancer deaths in women and is the second leading cause of death due to cancer in women — only surpassed by lung cancer.  

The statistics are not all bad. Breast cancer has decreased by 27% from 1990 to 2005. Five-year breast cancer survival rates are improving — 91% for Caucasian women and 78% for African-American women.

Weight contributes to breast cancer risk. Since 1960, the percentage of obesity has risen from 16% to 36% (2006). That means that 1/3 of the female population is obese. What a disturbing trend! And even worse, the trend of breast cancer has paralleled the obesity trend in women.

Here are the current Screening Guidelines:

• Yearly mammograms starting at age 40
• Clinical breast exam every 3 years for women in their 20’s and 30’s; annually after 40
• Self breast exams should begin in early 20’s

The focus in breast cancer today is on early detection and treatment.  At Seasons, we want to focus on prevention. Why ever let the cancer develop in the first place. Follow us over the next couple of weeks as we focus on how.

From the Doctor’s Desk: How Do I Detoxify? Detoxification Part 3

First of all, take a few minutes to read through my two previous posts: Detoxification Part 1 and  Detoxification Part 2. Part 3 of our detoxification series begins with a little chemistry lesson. Are you ready? Here we go. Let’s get down to the nuts and bolts of detoxification in the liver. By learning how the detoxification process works, we can learn the steps we need to take to detoxify.

As I mentioned in my earlier post, there are two basic parts to liver detoxification: Phase I and Phase II (this reminds me of Thing 1 and Thing II from the Dr. Seuss book I read to my kids).

Phase 1 Detoxification.

Phase 1 detoxification involves the cytochrome P450 system. Phase I detoxification involves oxidation, reduction, and hydrolysis. Phase I detoxification is always active and is very redundant.  What do I mean by redundant? There are a handful of enzymes in the CYP450 family that are utilized by over 200,000 substrates for oxidation, reduction and hydrolysis. In other words, many different chemicals or substrates will use the same CYP450 enzyme. A great picture of the redundancy is seen by clicking here.

Of note is the the CYP1A2 enzyme. This particular enzyme is responsible for metabolism of 40-50% of the drugs that we take. Do you remember the statistic from my earlier post? A leading cause of death is drug-to-drug interactions. Approximately 100,000 Americans die each year from adverse reactions to medications. If we are taking too many medications, then there is not enough CYP1A2 enzyme to adequately metabolize the drugs in the system leading to drug-to-drug interactions.

Let me give you some perspective. Drug interactions cause twice as many deaths as car accidents. And furthermore, hospital costs due to drug interactions have been estimated at between $1 and $4 billion annually. One of the big topics in the healthcare debate is controlling health care costs. Reducing deaths due to drug interactions looks like a good place to start, doesn’t it?

It doesn’t stop there. Phase I detoxification requires many cofactors: niacin, magnesium, copper, zinc, vitamin C, vitamins B2, B3, B6, B12, folic acid, and flavonoids. As you can see, vitamins are extremely important in the detox process. Without them, our bodies don’t work well. One more tidbit on vitamins — many causes of vitamin deficiencies today are the prescription medications we take — a double whammy!

Phase II Detoxification.

Phase II detoxification leads to further modification of the products of Phase I detoxification.  Large water-soluble molecules are added to the toxins through several different processes: glutathione conjugation, amino acid conjugation, methylation, sulfation, acetylation, and glucoronidation. In layman’s terms, after phase II modification, the body is able to eliminate the inactivated toxins via the bowels and/or bladder.

In summary, Phase I and Phase II enzymes are the power houses that detoxify our bodies of our daily toxin load. They are very dependent on vitamins, minerals, and energy. The many prescriptions we take lead to major drug interactions and vitamin depletions which interfere with our body’s ability to detoxify. Thus, if we are malnourished (typical American diet of fast food) and lack key vitamins and nutrients, then our body cannot adequately detoxify.  If we cannot detoxify, then we become inflamed. If we become inflamed, we develop disease.

So what next?  A shoe isn’t one-size-fits-all. And neither is detoxification. Assessment of your individual detoxification system and the build-up of toxins within your body will allow us to develop a customized detoxification process to fit your individual needs. Not only will we live healthier, disease-free lives through detoxification, but we will also save money! It all starts with a call. Make an appointment at Seasons join us on the path to wellness. Renew yourself.

From The Doctor’s Desk: Who Needs To Detoxify? Detoxification Part 2

Dr. Nathan Goodyear

Ever wonder if you need to detoxify? My first recommendation is look at and listen to your body.  The body will tell you if it is in trouble or imbalanced.  How? Physical signs or symptoms are our bodies’ message that all is not right. Here’s how to know if you bodies’ signs and symptoms are saying that you might be suffering from toxic build up. Here are some symptoms of toxin buildup.

• Headaches
• Muscle aches and pains
• Fatigue
• Asthma
• Allergies
• Skin disorders
• Chronic infections
• Altered mood
• Altered cognition
• Weight gain
• Altered stress tolerance
• Altered libido
• Infertility

Where do toxins in our bodies come from? Remember the quote from last week’s post? “For the first time in the history of the world, every human being is now subjected to contact with dangerous chemicals, from the moment of conception until death.  In the less than two decades of their use, the synthetic pesticides have been so thoroughly distributed throughout the animate and inanimate world that they occur virtually everywhere.”  — Rachel Carson from her book Silent Spring, published 1962.

Toxins are everywhere. The sources can range from toxins like Dioxins to prescription medication.  Adverse reactions to prescription drugs have been ranked as the 4^th to 6^th leading cause of death in the US according to the Journal of American Medical Association. This amounts to over 100,000 deaths per year.  The cause of adverse drug reactions is an overloaded pathway in Phase I of detoxification (CYP3A4), the pathway that detoxifies over 50% of all drugs in your system. The costs associated with adverse drug reactions has been estimated at up to $4 billion. With the rising costs of health care, treating the cause of these adverse drug reactions in addition to decreasing prescription drugs are two excellent ways to prevent complications and lower costs.

The most dangerous sources of toxins are environmental. Organochlorine pesticides, industrial chemicals, and unintended chemical byproducts surround us everyday and expose us to unwanted toxins. Widespread production of  pesticides began less than 80 years ago. Recently, the EPA estimated that more than 4 billion pounds of chemicals were released into the grounds natural water sources in the year 2000. In addition to pesticides and chemicals, the average American eats, unknowingly I might add, 124 pounds of additives per year. Frightening to think of it, isn’t it? And over 2.5 billion pounds of pesticides are used on crop lands, forests, lawns, and fields. The unfortunate fact is this: we live in a toxic world.

How can you decrease your daily exposure to toxins? Here are some great ways.

1. Avoid processed foods
2. Avoid fats
3. Avoid tap water — use filtered water
4. Avoid excess caffeine
5. Avoid excess alcohol
6. NO tobacco
7. Limit chronic medicine, if possible
8. Daily exercise
9. Avoid exposure in your workplace
10. Avoid living near industrial plants
11. Avoid liver dysfunction
12. Avoid kidney problems
13. Avoid intestinal dysfunction

The first ten suggestions are steps you and I can take every day to decrease our toxin exposure. But the last three require a bigger step: detoxification. By detoxifying your body, the liver, kidney, and intestines can operate more efficiently and effectively.

So, the question is not who needs detoxification, but who does NOT need detoxification?  The answer? EVERYONE will benefit from a periodic detoxification program.

From the Doctor’s Desk: The Sludge Pool of Toxins–Detoxification Part 1

“For the first time in the history of the world, every human being is now subjected to contact with dangerous chemicals, from the moment of conception until death.  In the less than two decades of their use, the synthetic pesticides have been so thoroughly distributed throughout the animate and inanimate world that they occur virtually everywhere.”

While this quote sounds like a line from a recent news report, it is actually an excerpt from Rachel Carson’s book Silent Spring published in 1962.

Detoxification seems to be a buzz word these days. Just google detoxification. You will find everything from water detoxification to colon cleanses.

So what is detoxification? The official definition of detoxification is this: the chemical changes of a xenobiotic, a phytochemical or an endogenous (one your own body makes) compound that renders it less toxic and ready to be excreted.  In layman’s terms, detoxification is the way our body protects us from things that we take in that could damage our body.

The ideal situation is toxins in and toxins out, right? If the body is working as designed, then it should be toxins in and toxins out. And how does the body get toxins out? There are many organs that detoxify.  The skin (through sweating), kidneys (through urination), but the liver is the most important detox organ.  The liver detoxification mechanism involves 2 main processes: Phase I and Phase II detoxification.

Phase I detoxification involves the cytochrome P-450 system in the liver. This is the first line of defense against all toxins.  Toxins are tagged and altered for further detoxification, which then occurs in Phase II.  Any break down in this process will result in increased toxin load on the body.  We will talk more in-depth about the detoxification process in my next two posts.

We are what we eat, drink, breath, and touch. But did you ever think that we are what we don’t eliminate? Without elimination of the toxic chemicals we take in and produce every day, our bodies swim in a sludge pool of toxins.

This increased toxic load on the body leads to  inflammation, the balance between pro-inflammatory and anti-inflammatory substances. The balance between Omega 6, a pro-inflammatory subtance, and Omega 3, an anti-inflammatory substance, is the perfect example.

It is the chronic imbalance of  pro-inflammatory substances that then leads to disease.

Shouldn’t the aim of all health care be to prevent inflammation and, therefore, disease? It is in fact, one of the main focuses of the Seasons approach to health and wellness.

In my next two posts, I will cover what detoxification is, who needs detoxification, and how one detoxifies.

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